Paroxysmal Nocturnal Hemoglobinuria (PNH)

CPT: Negative: 88184; 88185(x5); 88187; Positive: 88184; 88185(x7); 88187
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Test Details


  • PNH


The following markers are utilized to test neutrophils and/or monocytes: CD24, CD15, CD45, FLAER, CD64, CD14. If a PNH clone is identified, the following markers are used to test red blood cells: glycophorin A, CD59.


Samples with <1000 WBC/μL may only have RBC analysis reported.


Flow cytometry

Specimen Requirements


Peripheral blood


4 mL

Minimum Volume

2 mL


Green-top (heparin) tube (preferred) or lavender-top (EDTA) tube

Storage Instructions

Maintain specimen at room temperature; ship with cool pack.

Causes for Rejection

Specimens more than 48 hours old; specimens with viability <80%

Clinical Information

Special Instructions

Collect Monday through Thursday only. Specimens must arrive at Integrated Oncology—Brentwood or Phoenix—within 48 hours of collection.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
502251 Flow Cytometry PNH 502253 Interpretation: 33664-4
502251 Flow Cytometry PNH 502254 Comment: N/A
502251 Flow Cytometry PNH 502255 Specimen: 31208-2
502251 Flow Cytometry PNH 502256 Submitted Dx: N/A
502251 Flow Cytometry PNH 502257 Viability: 33194-2
502251 Flow Cytometry PNH 502259 Cell Population N/A
502251 Flow Cytometry PNH 502260 Granulocytes: 53831-4
502251 Flow Cytometry PNH 502262 Monocytes: 60554-3
502251 Flow Cytometry PNH 502261 Red Blood Cells: 49031-8
502251 Flow Cytometry PNH 502263 Representative Histograms: N/A
502251 Flow Cytometry PNH 502264 Antibodies Performed: N/A
502251 Flow Cytometry PNH 502274 Comment: N/A
502251 Flow Cytometry PNH 503332 Director Review 72486-4

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