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HLA DQB1*06:02 and HLA DQA1*01:02 are associated statistically with narcolepsy and are sometimes used as tests in support of that diagnosis.
Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, fresh specimens should be collected for retesting. Narcolepsy-associated HLA alleles are not diagnostic, but they are useful in stratifying risk.
Polymerase chain reaction (PCR)/sequence-specific oligonucleotide probes (Luminex®)
Whole blood or buccal swabs
7 mL or four buccal swabs
3 mL or four buccal swabs
Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). If submitting buccal swabs, please use the kit provided by LabCorp. To obtain the buccal swab kit or to discuss other specimen types, please telephone 800-533-1037.
Maintain specimen at room temperature. Protect from extreme heat or cold.
Causes for Rejection
Incorrect specimen container (tube type); yellow-top (ACD) tube
If you have questions, please telephone HLA customer service at 800-533-1037 for assistance in selecting the appropriate HLA test for the patient.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|167139||Narcolepsy Evaluation||167149||Please Note:||77202-0|