Lead, Whole Blood (Maternal)

CPT: 83655
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Test Details


Monitor maternal blood for environmental lead exposure. The Centers for Disease Control and Prevention recommends the following testing schedule for frequency of maternal blood lead follow-up during pregnancy.1 See table.

Result of Screening Test

Perform Diagnostic Test on Venous Blood

<5 μg/dL

No follow-up is indicated.

5−14 μg/dL

Within one month. Obtain a maternal BLL or cord BLL at delivery.

15−24 μg/dL

Within one month and then every two to three months. Obtain a maternal BLL or cord BLL at delivery.

25−44 μg/dL

Within one to four weeks and then every month. Obtain a maternal BLL or cord BLL at delivery. Within 24 hours and then at frequent intervals depending on clinical interventions and trends in BLL. Consultation with a clinician experienced in the management of pregnant women with BLLs in this range is strongly advised. Obtain a maternal BLL or cord BLL at delivery.


Atomic absorption spectrometry (AAS) or inductively coupled plasma/mass spectrometry (ICP/MS)

Specimen Requirements


Whole blood


3 mL

Minimum Volume

0.5 mL


Royal blue-top (EDTA) tube or tan-top lead-free tube; submit original unopened tube


Mix blood thoroughly to avoid clotting.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x2

Causes for Rejection

Clotted specimen

Clinical Information


1. Ettinger AS, Wengrovitz AG, eds. Guidelines for the Identification and Management of Lead Exposure in Pregnant and Lactating Women. Atlanta, Ga: Centers for Disease Control and Prevention, US Department of Health and Human Services; November 2010.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
700433 Lead, Maternal Blood 700440 Lead, Blood (Maternal) ug/dL 77307-7

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