Killer Immunoglobulin-like Receptors (KIR)

CPT: 81403
Print Share

Test Details

Synonyms

  • Genotyping
  • KIR
  • KIR Typing
  • Transplant

Use

The function of natural killer cells in the immune response is regulated by killer immunoglobulin-like receptors (KIR). These receptors interact with class I HLA antigens on the cell surface to prevent or activate killing of the target cell. KIR genotyping may be useful in some stem cell transplants because KIR matching or mismatching can mediate a graft-versus-leukemia effect when the cancer cells are underexpressing HLA class I antigens.

Limitations

Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

Specimen Requirements

Specimen

Whole blood

Volume

7 mL

Minimum Volume

3 mL

Container

Lavender-top (EDTA) tube

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Highly lipemic or hemolyzed specimen

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
168257 KIR Genotyping 64418-7 168258 2DL1 64413-8
168257 KIR Genotyping 64418-7 168259 2DL2 64414-6
168257 KIR Genotyping 64418-7 168262 2DL3 64415-3
168257 KIR Genotyping 64418-7 168263 2DL4 64416-1
168257 KIR Genotyping 64418-7 168264 2DL5 64419-5
168257 KIR Genotyping 64418-7 168265 2DS1 64420-3
168257 KIR Genotyping 64418-7 168266 2DS2 64421-1
168257 KIR Genotyping 64418-7 168267 2DS3 64422-9
168257 KIR Genotyping 64418-7 168268 2DS4 FUL 64423-7
168257 KIR Genotyping 64418-7 168269 2DS4 DEL 64424-5
168257 KIR Genotyping 64418-7 168270 2DS5 64425-2
168257 KIR Genotyping 64418-7 168271 3DL1 64426-0
168257 KIR Genotyping 64418-7 168272 3DL2 64427-8
168257 KIR Genotyping 64418-7 168273 3DL3 64428-6
168257 KIR Genotyping 64418-7 168274 3DS1 64429-4
168257 KIR Genotyping 64418-7 168275 2DP1 64430-2
168257 KIR Genotyping 64418-7 168276 3DP1 FUL 64431-0
168257 KIR Genotyping 64418-7 168277 3DP1 DEL 64432-8
168257 KIR Genotyping 64418-7 168278 Comment: N/A

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf