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Interleukin-10 (IL-10) is an important suppressor of immune responses1-3 In vitro studies indicate that IL-10 directly inhibits IL-2 and IL-5 production by TH1 and TH2 cells. IL-10 acts as an immunosuppressor of antigen presenting cells (APC). IL-10 suppresses epidermal Langerhans cell APC function, monocyte chemokines expression, and the bactericidal responses of macrophages. A number of studies suggest that IL-10 plays a role in controlling inflammation, autoimmunity, and angiogenesis.
Results of this test are for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Enzyme-linked immunosorbent assay (ELISA)
0.3 mL (Note: This volume does not allow for repeat testing.)
Lavender-top (EDTA) tube
Separate plasma from cells. Transfer plasma to a plastic transport tube.
Refrigerate; stable for 14 days. Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.
Causes for Rejection
Gross hemolysis; sample left on cells
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|140820||Interleukin-10, Plasma||26848-2||140821||Interleukin-10, Plasma||pg/mL||26848-2|