Interleukin-8, Plasma

CPT: 83520
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Test Details


  • CXCL8
  • IL-8
  • IL8


Interleukin-8 (IL-8), a member if the neutrophil-specific CXC subfamily of chemokines, is a potent neutrophil chemotactic and activating factor.1 It is a primary inflammatory cytokine produced by many cells (including monocytes/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, astrocytes, and chondrocytes) in response to proinflammatory stimuli such as bacteria and viruses. IL-8 serves to attract neutrophils to the site of inflammation and to activate them.


Results of this test are for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Enzyme-linked immunosorbent assay (ELISA)

Specimen Requirements




0.5 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Lavender-top (EDTA) tube


Separate plasma from cells. Transfer plasma transfer to a plastic transport tube.

Storage Instructions

Refrigerate; stable for seven days. Stable at room temperature for three days. Stable frozen for 14 days. Freeze/thaw cycles x2.

Causes for Rejection

Gross hemolysis; sample left on cells

Clinical Information


1. Mukaida N, Ketlinsky SA, Matsushima K. Interleukin-8. In: Thomson, AW and Lotze ME, eds. Cytokine Handbook. 4th ed, vol 2. London, UK, and San Diego, Calif: Academic Press, Elsevier Science; 2003: 1049-1081.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
140818 Interleukin-8, Plasma 33211-4 140819 Interleukin-8, Plasma pg/mL 33211-4

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