Immunohistochemical (Diagnostic) Staining Program

TEST: 484006
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CPT: 88342 (Immunohistochemistry or immunocytochemistry; each separately identifiable antibody per block, cytologic preparation or hematologic smear; first separately identifiable antibody per slide); 88341 (Immunohistochemistry or immunocytochemistry; each separately identifiable antibody per block, cytologic preparation or hematologic smear; each additional separately identifiable antibody per slide)
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Synonyms

  • Carcinoma Stains
  • Germ Cell Profile
  • Immunoperoxidase Stains
  • Lymphoma Markers
  • Mesothelioma Profile
  • Myeloma Profile
  • Thyroid Neoplasm Profile
  • Undifferentiated Tumor Profile

Test Includes

• Option I: Slides and controls are returned for your interpretation.

• Option II: Slides and controls are returned with an immunostain interpretation.

• Option IV: Full surgical pathology consultation (can be ordered with option II.)

For a complete list of individual stains and profiles see the Diagnostic Immunohistochemical Staining Program in the Oncology Appendix online.

Special Instructions

Clearly indicate program option being ordered. For program options II and IV, please submit an H&E slide and provide the following information: differential diagnosis, site of specimen, and clinical information. Please direct any questions regarding this test to oncology customer service at 800-345-4363.

Expected Turnaround Time

3 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

LabCorp Diagnostic Immunohistochemical Staining Program

    Specimen Requirements

    Specimen

    Formalin-fixed, paraffin-embedded (FFPE) tissue and/or slides sectioned from tissue block

    Volume

    One paraffin block and/or two unstained slides sectioned from tissue block for each requested stain

    Container

    Paraffin block transport pouch

    Collection

    Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.

    Storage Instructions

    Maintain specimen at room temperature.

    Test Details

    Use

    An extensive list of diagnostic immunohistochemical stains and profiles is available for the diagnosis of poorly differentiated tumors, identity of primary and metastatic tumors, and classification of lymphomas. Refer to the Diagnostic Immunohistochemical Staining Program in the Oncology Appendix online, or contact oncology customer service at 800-345-4363 for an updated list of immunostains.

    Limitations

    Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.

    Methodology

    Immunohistochemistry (IHC)

    LOINC® Map

    Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
    484006 Immunohistochemical Stain(s) 484010 Stain #1 N/A
    484006 Immunohistochemical Stain(s) 484011 Stain #2 N/A
    484006 Immunohistochemical Stain(s) 484012 Stain #3 N/A
    484006 Immunohistochemical Stain(s) 484013 Stain #4 N/A
    484006 Immunohistochemical Stain(s) 484015 Stain #5 N/A
    484006 Immunohistochemical Stain(s) 484016 Stain #6 N/A
    484006 Immunohistochemical Stain(s) 484017 Stain #7 N/A
    484006 Immunohistochemical Stain(s) 484018 Stain #8 N/A
    484006 Immunohistochemical Stain(s) 484019 Stain #9 N/A
    484006 Immunohistochemical Stain(s) 484023 Stain #10 N/A
    484006 Immunohistochemical Stain(s) 484026 Comment 77202-0

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    CPT Statement/Profile Statement

    The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf