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- CWD Resolution Typing
Test provides data for clients to use for matching transplant donors and recipients. Specific HLA A alleles may be correlated with certain disease states or other clinical conditions. This test may be used to identify specific alleles (except for HLA A*02:01 ).
CWD resolution typing for HLA will meet the following criteria:
1. The typing must contain only one unambiguously assigned genotype, or
2. The typing may contain multiple alternative genotypes if one includes two Common and Well Documented (CWD) alleles and the others do not include any CWD allele. Alleles that encode identical protein sequences in the antigen recognition site (ARS) will not be resolved even if they are CWD.
3. Rare or unusual allele combinations may not be ruled out.
4. Allele codes will be reported to include those alleles that are not ruled out.
Common and well documented alleles are defined by Cano et al1 and Mack et al.2
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution.
Lavender-top (EDTA) tube
Maintain specimen at room temperature; protect from extreme heat or cold. Do not freeze.
Causes for Rejection
Hemolyzed specimen; clotted specimen; wrong specimen container
If you have questions, please call 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|167331||HLA-A (CWD)||167384||HLA Methodology||49549-9|