Hepatitis C Virus (HCV) Genotyping With 1a Subtype Reflex to Hepatitis C Virus (HCV) GenoSure® NS3/4A

CPT: 87902. If reflex testing is performed, concomitant CPT codes/charges will apply.
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Test Details


Genotyping of the six major HCV types and their most common subtypes. Assessment of drug susceptibility by nucleic acid sequencing of a patient's hepatitis C virus (HCV) to the NS3/4A protease inhibitors. Detects Q80K polymorphism.


This procedure may not be successful when the HCV viral load is <1000 IU/mL in serum or plasma.


Polymerase chain reaction (PCR) amplification and solid-phase electrochemical detection

Specimen Requirements


Serum or plasma, frozen


3 mL

Minimum Volume

2 mL


Ship in plasma preparation tubes (PPT™) or screw-capped polypropylene frozen transport tubes.


Collect specimen in two PPT™ tubes, gel-barrier tubes, yellow-top (ACD) tubes, or lavender-top (EDTA) tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection, remove serum/plasma, and transfer specimen to polypropylene screw-capped tubes, and freeze. Specimens drawn into PPT™s need to be centrifuged within six hours and frozen. Ship frozen. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Maintain frozen at -20°C.

Causes for Rejection

Hemolysis; green-top (heparin) tube; specimen not frozen on date of collection; PPT™ not centrifuged; specimen received in "pop-top" or "snap-cap" tube; specimen shipped at room temperature

Clinical Information

Special Instructions

A separate frozen specimen is required for each frozen test ordered. The HCV GenoSure® NS3/4A assay is only validated for samples with HCV viral load >2000 IU/mL.

For Providers

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CPT Statement/Profile Statement

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