Everolimus, Whole Blood

CPT: 80169
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Expected Turnaround Time

2 - 4 days

Related Documents

Specimen Requirements


Whole blood


2 mL

Minimum Volume

0.50 mL


Lavender-top (EDTA) tube or green-top (heparin) tube

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Test Details


Everolimus is a proliferation signal inhibitor that prevents allograft rejection. It exerts its immunosuppressive effect by inhibiting the proliferation, and thus clonal expansion, of antigen-activated T cells, which is driven by T-cell-specific interleukins. Everolimus inhibits an intracellular signaling pathway that is triggered up binding of these T-cell growth factors to their respective receptors, and which normally leads to cell proliferation. The blockage of this signal by everolimus leads to an arrest of the cells at the G1 stage of cell cycle.


This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Tedesco-Silva H Jr, Felipe CR, Freitas TVS, Cristeli MP, Rodrigues CA, Pestana JOM. Impact of everolimus: Update on immunosuppressive therapy strategies and patient outcomes after renal transplantation. Transplant Res Risk Management. 2011; 3:9-29.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
700003 Everolimus 50544-6 700004 Everolimus ng/mL 50544-6

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