Ethyl Benzene Metabolite Profile, Urine

CPT: 82570; 83921
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Test Details

Test Includes

Creatinine, urine; mandelic acid, urine; mandelic acid:creatinine ratio


Monitor exposure to ethyl benzene


Gas chromatography (GC)

Reference Interval

Environmental exposure: None detected

Occupational exposure: BEI® (sampling time is the end of shift at the end of the work week): 700 mg/g creatinine1

Additional Information

BEI® are reference values intended as guidelines for evaluation of occupational exposure. BEI® represent biological levels of chemicals that correspond to workers with inhalation exposure equivalent to the threshold limit value (TLV®) of the chemicals. TLVs refer to the airborne concentrations of substances and represent conditions under which it is believed that nearly all workers may be repeatedly exposed, day after day, without adverse health effects.1

Specimen Requirements




5 mL

Minimum Volume

2.2 mL


Plastic urine container, no preservative


Sampling time is the end of the shift at the end of the work week for industrial exposure monitoring. Metabolites with timing “end of shift at the end of the work week” (meaning four or five consecutive working days with exposure) are eliminated with half-lives longer than five hours. Such metabolites accumulate in the body during the work week; therefore, their timing is critical in relation to previous exposures.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

7 days


14 days


14 days

Clinical Information


1. TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices 2010, American Conference of Governmental Industrial Hygienists (ACGIH).


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
723486 Ethylbenzene Metabolite PRF, U 723321 Mandelic Acid, Urine mg/L 13000-5
723486 Ethylbenzene Metabolite PRF, U 723280 Creatinine(Crt),U g/L 2161-8
723486 Ethylbenzene Metabolite PRF, U 723326 Mandelic/Creat Ratio mg/g Crt 13001-3

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