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Enterohemorrhagic E coli (EHEC) Shiga Toxin, EIA
- E coli O157
- EHEC, Stool Culture
- Shiga Toxin
Detect the presence of Shiga-toxin-producing enterohemorrhagic E coli
There are four types of pathogenic E coli (see table). This test detects only enterohemorrhagic E coli; tests are not available for the other pathogenic E coli.
Travelers' diarrhea and infant diarrhea in less developed countries
Hemolytic uremic syndrome
Thrombotic thrombocytopenia purpura
Detection of enterohemorrhagic E coli Shiga toxins by enzyme immunoassay (EIA)
No enterohemorrhagic E coli Shiga toxin detected
Treatment of patients infected with Enterohemorrhagic E coli (EHEC) with antibiotics is contraindicated. Hemorrhagic colitis can be differentiated from other causes of diarrhea by its progression from watery to bloody diarrhea during a few days' time. Fecal leukocytes are markedly increased. Fever is usually absent. The disease is mediated by the production of a Shiga-like toxin that interferes with colonic brush border cells, protein synthesis, and ultimately causes cell death. Enterohemorrhagic E coli (EHEC) differ from other strains of bacteria in the large amount of toxin they produce. Virtually all O157:H7 organisms and other EHEC strains have been shown to produce Shiga toxin.
Stool or rectal swab placed in stool culture transport vial
1 to 2 g, 1 to 2 mL, or one swab
Rectal swab with obvious stool
Stool culture transport vial; culture collection swab may be used to collect rectal swabs or a swab of fecal material, then swab should be placed in stool culture transport vial (Para-Pak® orange).
Maintain specimen at room temperature.
Causes for Rejection
Specimen received in grossly leaking transport container; diapers; dry specimen; specimen submitted in fixative or additive; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions (not in a C&S vial or in an overfilled C&S vial); specimen received after prolonged delay in transport (usually more than 72 hours); specimen stored or transported frozen; wooden shaft swab in transport device; unlabeled specimen or name discrepancy between specimen and request label
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|180935||E coli Shiga Toxin EIA||21262-1||180935||E coli Shiga Toxin EIA||21262-1|