Drug Screen, Serum and Whole Blood

CPT: 80184; 80299; 80320; 80345; 80346
Print Share

Test Details

Test Includes

Acetone; butalbital; chlordiazepoxide; diazepam; ethanol; isopropanol; methanol; norchlordiazepoxide; nordiazepam; pentobarbital; phenobarbital; salicylates


This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Liquid chromatography/tandem mass spectrometry (LC/MS-MS), gas chromatography, spectrophotometry, and immunoassay

Specimen Requirements


Serum and/or whole blood


4 mL serum and/or 7 mL whole blood

Minimum Volume

1.5 mL serum and/or 0.5 mL whole blood


Red-top tube and/or gray-top (sodium fluoride) tube


Separate serum from cells and transfer to a plastic transport tube. Submit full, unopened gray-top tube for analysis of volatiles. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Storage Instructions


Causes for Rejection

Gel tube; hemolysis; gross lipemia; icteric specimen

Clinical Information

Special Instructions

Sample is tested for the presence of the substances listed above (see Test Includes). Drugs will be quantitated; please indicate suspected substance, if possible.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
007034 Drug Screen (Blood or Serum) 007066 Acetone % 5568-1
007034 Drug Screen (Blood or Serum) 007063 Ethanol % 56478-1
007034 Drug Screen (Blood or Serum) 007064 Isopropanol % 5669-7
007034 Drug Screen (Blood or Serum) 007065 Methanol % 5693-7
007034 Drug Screen (Blood or Serum) 017194 Pentobarbital ug/mL 3924-8
007034 Drug Screen (Blood or Serum) 017210 Phenobarbital ug/mL 3948-7
007034 Drug Screen (Blood or Serum) 072181 Butalbital ug/mL 6895-7
007034 Drug Screen (Blood or Serum) 716035 Chlordiazepoxide ug/mL 3457-9
007034 Drug Screen (Blood or Serum) 716043 Norchlordiazepoxide ug/mL 9776-6
007034 Drug Screen (Blood or Serum) 716050 Nordiazepam ug/mL 3537-8
007034 Drug Screen (Blood or Serum) 716068 Diazepam ug/mL 3548-5
007034 Drug Screen (Blood or Serum) 700013 Salicylates ug/mL 4024-6
007034 Drug Screen (Blood or Serum) 700473 Disclaimer: N/A
Reflex Table for Butalbital
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 700473 Disclaimer: 700473 Disclaimer: N/A

For Providers

Please login to order a test.


© 2018  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf