Diphtheria Antitoxoid Antibodies

CPT: 86317
Print Share

Test Details

Synonyms

  • Diphtheria Antibodies
  • Diphtheria Toxin Antibodies

Use

Assess immunity against diphtheria by determining levels of circulating antibodies to diphtheria toxin or to measure the immune response, postvaccination, in individuals suspected of immunodeficiency disorders

Limitations

This procedure is rarely used for confirmation of diphtheria infection; it cannot accurately discriminate antibodies between 0.10 IU/mL and 0.01 IU/mL. Immunity declines with age.

This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.

Methodology

Enzyme immunoassay (EIA)

Reference Interval

• Nonprotective: <0.1 IU/mL

• Protective: ≥0.1 IU/mL

Specimen Requirements

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.25 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

Unstable

Causes for Rejection

Gross hemolysis; lipemia; bacterial contamination

Clinical Information

References

Rose NR, Manual of Clinical Immunology, 5th ed, Washington, DC: ASM Press, 1997, 465-9.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
163709 Diphtheria Antitoxoid Ab 5116-9 163710 Diphtheria Antitoxoid Ab IU/mL 5116-9

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf