Chromosome Analysis, Solid Tumor

TEST: 510995
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CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Test Includes

Enzyme digestion of tissue; primary culturing; chromosome harvesting; banding; analysis (20 metaphases); and karyotyping

Special Instructions

Fluorescence in situ Hybridization (FISH), Oncology [510669] of a formalin-fixed, paraffin block is the test of choice for FNAs/core biopsies. Indicate tumor type on the test request form. Please direct any questions regarding this test to oncology customer service at 800-345-4363.

Expected Turnaround Time

10 - 14 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Sterile, non-necrotic tumor tissue

Volume

0.5 to 1 cm3 tissue

Container

Lymph node transport bottle or sterile tube containing Ringer's lactate

Collection

Submit at room temperature using Lymph Node Transport Kit (supplied by LabCorp). Specimens should arrive in the laboratory within 48 hours of collection. Indicate date and time of collection on the request form.

Storage Instructions

Maintain specimen at room temperature (refrigerate if sterility is questionable).

Causes for Rejection

Gross contamination; frozen specimen; fixed specimen

Test Details

Use

Detection of chromosomal abnormalities with subgroup-specific diagnostic and prognostic significance (eg, t(11;22) in Ewing sarcoma)

Methodology

Enzymatic digestion of tissue; in situ culturing and harvesting with G-banding

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510995 Chromosome, Solid Tumor 510932 Specimen Type 31208-2
510995 Chromosome, Solid Tumor 510933 Cells Counted 62361-1
510995 Chromosome, Solid Tumor 510934 Cells Analyzed 62360-3
510995 Chromosome, Solid Tumor 510935 Cells Karyotyped 55199-4
510995 Chromosome, Solid Tumor 510936 GTG Band Resolution Achieved 62358-7
510995 Chromosome, Solid Tumor 510937 Cytogenetic Result 62356-1
510995 Chromosome, Solid Tumor 510983 Interpretation 62365-2
510995 Chromosome, Solid Tumor 510984 Director Review: 48672-0
510995 Chromosome, Solid Tumor 512123 PDF 51967-8

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