Chromosome Analysis, Prenatal Cordocentesis and Fetal Hemoglobin

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Test Details

Synonyms

  • Karyotyping
  • Percutaneous Umbilical Cord Sampling (PUBS)

Use

Rapid analysis of fetal chromosomes, used most frequently following the determination of fetal amniocyte mosaicism

Methodology

Standard G-banded karyotyping and isoelectric focusing of hemoglobin to confirm fetal derivation of the sample

Specimen Requirements

Specimen

Fetal blood

Volume

1 to 3 mL

Minimum Volume

0.5 mL

Container

Green-top (sodium heparin) pediatric tube

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Specimen frozen; clotted specimen; specimen determined to be maternal in origin

Clinical Information

Special Instructions

Medical indication for procedure and the patient's name and age should be included on the request form.

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