Chimerism Analysis With CD33/CD66b Cells (Transplant Monitoring)

CPT: 81268(x2)
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Test Details


  • Cell Sorting CD33/CD66b
  • Chimerism Analysis With Sorted Myeloid Cells
  • Engraftment Monitoring Sorted Myeloid Cells


Monitor the level of donor CD33/CD66b cells in the recipient (patient-host) of a hematopoietic stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used as a reference for the evaluation.


This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Antibody-mediated positive selection of CD33/CD66 cells and separation with magnetic nanoparticles. DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)

Specimen Requirements


Whole blood


6 mL

Minimum Volume

2 mL


Yellow-top (ACD-A or ACD-B) tube

Patient Preparation


Storage Instructions

Maintain specimen at room temperature. Do not refrigerate or freeze.

Causes for Rejection

Improper collection tube (ie, EDTA or heparin); hemolysis; clotted specimen

Clinical Information

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service. Ship specimen to arrive in the laboratory between Monday and Friday.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
176079 Chimerism Anal CD33/CD66b Cell 176138 Donor 1 N/A
176079 Chimerism Anal CD33/CD66b Cell 176373 Donor 2 N/A
176079 Chimerism Anal CD33/CD66b Cell 176374 Donor 3 N/A
176079 Chimerism Anal CD33/CD66b Cell 176375 Donor 4 N/A

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The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at