Chimerism Analysis With CD33/CD66b Cells (Transplant Monitoring)

TEST: 176079
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CPT: 81268(x2)
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Synonyms

  • Cell Sorting CD33/CD66b
  • Chimerism Analysis With Sorted Myeloid Cells
  • Engraftment Monitoring Sorted Myeloid Cells

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service. Ship specimen to arrive in the laboratory between Monday and Friday.

Expected Turnaround Time

3 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

For more information, please view the literature below.

Transplant Engraftment (Chimerism Testing)

Specimen Requirements

Specimen

Whole blood

Volume

6 mL

Minimum Volume

2 mL

Container

Yellow-top (ACD-A or ACD-B) tube

Storage Instructions

Maintain specimen at room temperature. Do not refrigerate or freeze.

Patient Preparation

None

Causes for Rejection

Improper collection tube (ie, EDTA or heparin); hemolysis; clotted specimen

Test Details

Use

Monitor the level of donor CD33/CD66b cells in the recipient (patient-host) of a hematopoietic stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used as a reference for the evaluation.

Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).

Methodology

Antibody-mediated positive selection of CD33/CD66 cells and separation with magnetic nanoparticles. DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
176079 Chimerism Anal CD33/CD66b Cell 176138 Donor 1 N/A
176079 Chimerism Anal CD33/CD66b Cell 176373 Donor 2 N/A
176079 Chimerism Anal CD33/CD66b Cell 176374 Donor 3 N/A
176079 Chimerism Anal CD33/CD66b Cell 176375 Donor 4 N/A

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