Chimerism Analysis With CD3 Cells (Transplant Monitoring)

CPT: 81268
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Test Details


  • Cell Sorting CD3
  • Chimerism Analysis With Sorted Lymphoid Cells
  • Engraftment Monitoring Sorted Lymphoid Cells


Monitor the level of donor CD3+ cells in the recipient (patient-host) of a stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used as a reference for the evaluation.


This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Antibody-mediated positive selection of CD3+ cells and separation with magnetic nanoparticles. DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)

Specimen Requirements


Whole blood


6 mL

Minimum Volume

2 mL


Yellow-top (ACD-A or ACD-B) tube

Patient Preparation


Storage Instructions

Maintain specimen at room temperature. Do not refrigerate or freeze. Ship specimen to arrive in the laboratory between Monday and Friday.

Causes for Rejection

Improper collection tube (ie, EDTA or heparin); hemolysis; clotted specimen

Clinical Information

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
176059 Chimerism Analysis CD3 Cells 176129 Donor 1 N/A
176059 Chimerism Analysis CD3 Cells 176231 Donor 2 N/A
176059 Chimerism Analysis CD3 Cells 176232 Donor 3 N/A
176059 Chimerism Analysis CD3 Cells 176233 Donor 4 N/A

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