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- Free Buprenorphine
Buprenorphine is used in the management of moderate to severe chronic pain.
Half-life elimination: IV: 2.2 to 3 hours, Sublingual tablet: approximately 37 hours, Transdermal patch: approximately 26 hours
Time to peak plasma: Sublingual: 30 minutes to 1 hour
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Serum, plasma, or whole blood
Red-top tube, lavender-top (EDTA) tube, gray-top (sodium fluoride) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Separate serum or plasma within two hours of collection and transfer to a plastic transport tube.
Causes for Rejection
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|070103||Buprenorphine and Metabolite||070101||Buprenorphine||ng/mL||3413-2|
|070103||Buprenorphine and Metabolite||070102||Norbuprenorphine||ng/mL||53881-9|