Find Locations
For hours, walk-ins and appointments.Synonyms
- Buprenex®
- Free Buprenorphine
- Subutex®
Expected Turnaround Time
3 - 6 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum, plasma, or whole blood
Volume
0.25 mL
Minimum Volume
0.1 mL
Container
Red-top tube, lavender-top (EDTA) tube, gray-top (sodium fluoride) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Collection
Separate serum or plasma within two hours of collection and transfer to a plastic transport tube.
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Causes for Rejection
Gel-barrier tube
Test Details
Use
Buprenorphine is used in the management of moderate to severe chronic pain.
Half-life elimination: IV: 2.2 to 3 hours, Sublingual tablet: approximately 37 hours, Transdermal patch: approximately 26 hours
Time to peak plasma: Sublingual: 30 minutes to 1 hour
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
References
Drug Information Handbook. 24th ed. Hudson, OH: Wolters Kluwer Clinical Drug Information, Inc; 2015; 300-304.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 070103 | Buprenorphine and Metabolite | 75368-1 | 070101 | Buprenorphine | ng/mL | 75368-1 |
| 070103 | Buprenorphine and Metabolite | 75368-1 | 070102 | Norbuprenorphine | ng/mL | 75370-7 |
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