Bleeding Diathesis With Normal aPTT/PT Profile (Esoterix)

TEST: 503541
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CPT: 85240(x2); 85245; 85246; 85250; 85270; 85290; 85360; 85384; 85410; 85415
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Test Includes

α2-Antiplasmin assay; euglobulin lysis time; factor VIII activity; factor VIII chromogenic; factor IX activity; factor XI activity; factor XIII activity; fibrinogen activity; PAI-1 activity with reflex to PAI-1 antigen and tissue plasminogen activator (tPA); von Willebrand factor activity; von Willebrand factor antigen

Expected Turnaround Time

7 - 15 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

Procedures for Hemostasis and Thrombosis: A Clinical Test Compendium

    Specimen Requirements

    Specimen

    Plasma, frozen

    Volume

    7 mL platelet-poor frozen citrated plasma divided into seven tubes

    Container

    Blue-top (sodium citrate) tube

    Collection

    Plasma must be separated from cells within 45 minutes of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed.

    Storage Instructions

    Freeze.

    Causes for Rejection

    Noncitrated plasma; gross hemolysis; fibrin clot in plasma

    Test Details

    Use

    To assist in the determination of a cause of bleeding in a patient with normal aPTT and PT.

    Limitations

    This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.

    Methodology

    See individual tests.

    LOINC® Map

    Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
    503541 Bleeding Diathesis 500666 Factor VIII Activity % 3209-4
    503541 Bleeding Diathesis 500193 FVIII Chromogenic % 49865-9
    503541 Bleeding Diathesis 500672 Factor IX Activity % 3187-2
    503541 Bleeding Diathesis 500674 Factor XI Activity % 3226-8
    503541 Bleeding Diathesis 500186 Factor XIII Activity** % 27815-0
    503541 Bleeding Diathesis 500701 Fibrinogen Activity mg/dL 3255-7
    503541 Bleeding Diathesis 500669 von Willebrand Factor Activity % 6014-5
    503541 Bleeding Diathesis 500668 von Willebrand Factor Antigen % 27816-8
    503541 Bleeding Diathesis 501175 Alpha-2 Antiplasmin Assay % 27810-1
    503541 Bleeding Diathesis 500616 PAI-1 Activity IU/mL 5975-8
    503541 Bleeding Diathesis 503479 Euglobulin Lysis Time 40454-1
    Reflex Table for PAI-1 Activity
    Order Code Order Name Result Code Result Name UofM Result LOINC
    Reflex 1 503551 PAI-1+TPA Ag 500030 TPA Antigen ng/mL 5971-7
    Reflex Table for PAI-1 Activity
    Order Code Order Name Result Code Result Name UofM Result LOINC
    Reflex 1 503551 PAI-1+TPA Ag 500059 PAI-1 Antigen ng/mL 22758-7

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