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Bacterial Vaginosis (Sialidase), Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, NAA, Vaginal Yeast Culture
- BV (Sialidase), Ct/Ng/Tv (NAA), Vaginal Yeast (Culture)
BV (sialidase) activity: Enzyme activity test for use in the detection of vaginal fluid specimens for sialidase activity, an enzyme produced by bacteria associated with bacterial vaginitis, including Bacteroides spp, Prevotella spp, and Mobiluncus spp, and some G vaginalis. In a recent study, Bradshaw et al demonstrated the test to be 88% sensitive and 95% specific.
Vaginal yeast culture: Detect yeast in vaginal fluid
Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis by NAA: Diagnosis of C trachomatis, N gonorrhoeae, and T vaginalis infections
BV (sialidase) activity: Collecting specimens from the cervix should be avoided because (a) it might increase the risk to OB patients, and (b) cervical sialidase activity is usually higher than vaginal sialidase activity. Do not collect specimens from patients who have (a) used a vaginal cream or ointment product, (b) douched, or (c) used spermicides, vaginal lubricants, or feminine sprays within 72 hours of testing. If insufficient sample is collected or collected from a patient undergoing antimicrobial therapy, the test may yield a false-negative result.
BV (sialidase) activity: chromogenic enzyme activity test; vaginal yeast culture: culture; C trachomatis, N gonorrhoeae, T vaginalis by NAA: nucleic acid amplification (NAA)
Multiple swab specimens
Copan double swab in Amies liquid medium and Aptima® unisex swab transport
Using transport swabs provided, collect vaginal fluid sample by contacting the lower one-third of the vaginal wall, rotating for 10 to 20 seconds to absorb fluid. Immediately place the swabs into the transport tubes. For the Aptima® swab, carefully break the swab shaft against the side of the tube. Tightly screw on the cap.
Maintain specimen at room temperature or refrigerate (2°C to 30°C).
Causes for Rejection
Specimen collected or transport other than previously described; unlabeled specimens or those with a discrepancy between the specimen label and the test request form; Aptima® Combo 2 (AC2) swab specimen transport tube with two swabs or swab not supplied by Gen-Probe® or no swab; UTM transport from an inappropriate site; vaginal swab devices from patients younger than 16 years of age; ProbeTec™ swabs.
Note: Specimens collected from children younger than 13 years of age or specimens submitted without the age of the patient or date of birth may be tested and will be reported with a disclaimer.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|182725||BV+Ct/Ng/Tv NAA+Yeast Culture||180036||BV, Sialidase Activity||41477-1|
|182725||BV+Ct/Ng/Tv NAA+Yeast Culture||182495||Vaginal Yeast Culture||18483-8|
|182725||BV+Ct/Ng/Tv NAA+Yeast Culture||183161||Chlamydia by NAA||43304-5|
|182725||BV+Ct/Ng/Tv NAA+Yeast Culture||183162||Gonococcus by NAA||43305-2|
|182725||BV+Ct/Ng/Tv NAA+Yeast Culture||188053||Trich vag by NAA||70165-6|