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- Flow Crossmatch
- HLA Crossmatch
- T-Cell and B-Cell Crossmatch
Detection of the presence of antidonor antibodies (HLA) in a potential solid organ recipient, T- and B-cell crossmatch detects the presence of anti-Class I/Class II HLA antibodies in the recipient that would recognize donor-specific antigens. The presence of antibodies against donor HLA antigens is a contraindication for transplantation and could lead to immediate/acute organ rejection.
Although the primary antibodies that are detected by this assay are to HLA, other non-HLA-specific antibodies could cause positive T- and/or B-cell crossmatch. This testing only demonstrates antibodies that recognize donor antigens and cannot distinguish clinical relevant antibodies (eg, complement binding ability) from nonclinical antibodies. This assay only detects the presence of IgG antidonor antibodies and does not detect IgM or other immunoglobulin subclasses.
Presence of antibody bound to human lymphocytes detected by immunofluorescence and flow cytometry
Donor sample: Whole blood; Recipient sample: Serum
Donor sample: 12 mL; Recipient sample: 2 mL
Donor sample: 8 mL; Recipient sample: 2 mL
Causes for Rejection
To schedule this test, you must telephone 800-533-1037, HLA customer service.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|167160||Allo-Crossmatch by Flow||167191||AlloCrossmatch T-Cell(ALTCELL)||48409-7|
|167160||Allo-Crossmatch by Flow||167192||AlloCrossmatch B-Cell(ALBCELL)||48390-9|