Abnormal PT/aPTT Reflexive Profile (Esoterix)

CPT: 80500; 85610; 85613(x2); 85670; 85730
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Test Details

Test Includes

Activated partial thromboplastin time (aPTT); dilute Russell's viper venom time (dRVVT); international normalized ratio (INR); pathologist interpretation; prothrombin time; thrombin time

Methodology

See individual tests.

Specimen Requirements

Specimen

Citrated plasma, frozen

Volume

Three 1 mL platelet-poor frozen tubes

Container

Blue-top (sodium citrated) tubes

Patient Preparation

Ideally the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to the test and heparin, direct Xa and thrombin inhibitor therapies for about three days prior to testing.

Collection

Plasma must be separated from cells within 45 minutes of venipuncture and centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Freeze.

Clinical Information

Special Instructions

• If PT is >3 seconds above the upper limit of normal, the test will reflex to PT mixing studies and factor VII activity.

• If aPTT is >5 seconds above the upper limit of normal, the test will reflex to aPTT mixing studies, hexagonal phospholipid neutralization, factor XI activity, factor IX activity, and factor VIII activity.

• If TT is abnormal, the test will reflex to fibrinogen activity and fibrinogen antigen.

• If reflex testing is performed, concomitant CPT codes/charges will apply.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
503335 Abn PTT/APTT Reflexive Panel 500230 Thrombin Time sec 3243-3
503335 Abn PTT/APTT Reflexive Panel 500372 Prothrombin Time sec 5902-2
503335 Abn PTT/APTT Reflexive Panel 500682 INR ratio 6301-6
503335 Abn PTT/APTT Reflexive Panel 500513 APTT sec 14979-9
503335 Abn PTT/APTT Reflexive Panel 501549 DRVVT Screen Seconds sec 6303-2
503335 Abn PTT/APTT Reflexive Panel 501548 DRVVT Confirm Seconds sec 57838-5
503335 Abn PTT/APTT Reflexive Panel 500585 DRVVT Ratio ratio 50410-0
503335 Abn PTT/APTT Reflexive Panel 500684 Pathologist Interpretation 21026-0
503335 Abn PTT/APTT Reflexive Panel 502454 Abn PTT/APTT Reflexive Panel N/A
Reflex Table for Thrombin Time
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502451 Fibrinogen Activity+Antigen 500701 Fibrinogen Activity mg/dL 3255-7
Reflex Table for Thrombin Time
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502451 Fibrinogen Activity+Antigen 500702 Fibrinogen Antigen mg/dL 42772-4
Reflex Table for Prothrombin Time
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502453 FVII Act+PT 1:1 NP 500373 PT 1:1 NP sec 5959-2
Reflex Table for Prothrombin Time
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502453 FVII Act+PT 1:1 NP 500679 Factor VII Activity % 3198-9
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500363 APTT 1:1 NP sec 5946-9
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500364 APTT 1:1 Saline Sec 43734-3
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500666 Factor VIII Activity % 3209-4
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500672 Factor IX Activity % 3187-2
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500674 Factor XI Activity % 3226-8
Reflex Table for APTT
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 502452 Reflexive Profile Building Blk 500569 Hexagonal Phospholipid Neutral sec 3282-1

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The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf