Anti-U2 RNP Ab (RDL)

CPT: 86235
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Synonyms

  • Anti-U2 small nuclear ribonucleoprotein (snRNP)
  • snRNP
  • U2

Expected Turnaround Time

14 - 21 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Refrigerate or freeze.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types


Test Details


Use

U2 snRNP autoantibodies, known as a type of myositis-associated autoantibodies (MSAs) are frequently, but not exclusively, in patients with myositis. MSAs include autoantibodies to U1-RNP, U2-RNP, PM/SCL and Ku.


Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

RIPA Gel Radiography


Reference Interval

Negative


Additional Information

<5% of IIM; scleroderma/myositis overlap syndrome


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520024 Anti-U2 RNP Ab (RDL) 68549-5 520025 Anti-U2 RNP Ab (RDL) 68549-5

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