Find Locations
For hours, walk-ins and appointments.Test Includes
aPTT; factor VIII activity; factor VIII chromogenic; pathologist interpretation
Expected Turnaround Time
4 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Plasma
Volume
4 mL platelet-poor, frozen, citrated plasma divided into two tubes
Minimum Volume
2 mL
Container
Blue-top (sodium citrate) tube
Collection
Plasma must be separated from cells within three hours of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within four hours and keep frozen until testing is performed.
Storage Instructions
Freeze
Causes for Rejection
Noncitrated plasma; gross hemolysis; fibrin clot in plasma; sample received thawed
Test Details
Use
This profile is appropriate for the evaluation of individuals suspected of or previously identified as having nonsevere (mild or moderate) hemophilia A, in order to determine if there is a twofold discrepancy in the one stage and chromogenic factor VIII activities as has been described in discrepant hemophilia A. Evaluation for nonsevere hemophilia A using a one stage (clot-based) activity assay only may lead to missed diagnosis or misclassification of disease severity.
Methodology
See individual tests.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 504297 | Non-Severe Hemophilia A Prof. | 500513 | APTT | sec | 14979-9 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500666 | Factor VIII Activity | % | 3209-4 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500193 | FVIII Chromogenic | % | 49865-9 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500684 | Pathologist Interpretation | 21026-0 |
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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf