Allergy Components

IgE allergen component testing may be helpful in those cases wherein clinicians need to identify and quantify the IgE levels of the parts or components of a suspected, offending allergen that trigger genuine allergic sensitization and likely severe, systemic reaction and those that may produce cross-reactive sensitization and decreased clinical responsiveness.

Knowing this information may assist with management decisions, such as1:

  • Patient risk assessment and stratification for procedures such as food challenge testing,
  • Patient counseling on allergen exposure reduction and/or avoidance, or
  • Patient selection and selection of specific allergen(s) for immunotherapy.

As with any allergy testing, it is important to stress the importance of evaluating allergen component test results within the context of the patient’s history, as allergen IgE sensitization does not necessarily equate to clinical responsiveness; and each allergic patient responds individually to exposure to various allergen sources, creating his or her own distinct IgE antibody molecular “profile”.1

For general test requirements, such as specimen, volume, container, storage and methodology, please click on the test number below to visit each individual test page.

Test Name

Test Number

Profile includes

Allergen Profile, Nut, IgE With Component Reflexes*

604764

Almond, Brazil Nut, Cashew Nut, Hazelnut (Filbert), Macadamia Nut, Peanut (Whole), Pecan, Pistachio, Walnut

Allergen Profile, Brazil Nut, IgE With Component Reflexes*

603972

Brazil Nut

Allergen Profile, Cashew Nut, IgE With Component Reflex*

604159

Cashew Nut

Allergen Profile, Hazelnut, IgE With Component Reflexes*

604734

Hazelnut

Allergen Profile, Peanut, IgE With Component Reflexes*

603916

Peanut (Whole)

Allergen Profile, Peanut, IgE With Components

603904

Peanut (Whole)

Allergen Profile, Milk Component IgE

603849

Alpha-lactalbumin, Beta-lactoglobulin, and Casein IgE

Allergen Profile, Milk, IgE With Component Reflexes*

603927

Milk IgE (If milk IgE is ≥0.35 kU/L, then reflex testing is completed for Alpha-lactaalbumin, Beta-lactoglobulin, and Casein IgE)

Allergen Profile, Egg Component IgE

603833

Ovalbumin IgE and Ovomucoid IgE

Allergen Profile, Egg White, IgE With Component Reflexes*

603940

Egg white IgE (If egg white is ≥0.35 kU/L, then reflex testing is completed for Ovalbumin IgE and Ovomucoid IgE)

Allergen Profile, Food IgE With Component Reflexes*   

603834

Clam; codfish; corn; egg white; milk; peanut (whole); scallop; sesame seed; shrimp; soybean; walnut; wheat

Allergen Profile, Food IgE II With Component Reflexes*  

604783

Almond; Brazil nut; cashew nut; clam; codfish; corn; egg white; hazelnut (filbert); macadamia nut; milk; peanut (whole); pecan; pistachio; scallop; sesame seed; shrimp; soybean; walnut; wheat

Allergen Profile, Food-Basic IgE With Component Reflexes*   

603857

Codfish; cow’s milk; egg white; peanut (whole); soybean; wheat

Allergen Profile, IgE (Pediatric) With Component Reflexes* 

604771

Almond; Brazil nut; cashew nut; cat dander; Cladosporium herbarum; cockroach (German); codfish; D farina; D pteronyssinus; dog dander; egg white; hazelnut (filbert); macadamia nut; milk; mouse urine; peanut (whole); pecan; pistachio; scallop; sesame seed; shrimp; soybean; walnut; wheat

Allergen Profile Plus IgE (Pediatric) With Component Reflexes*  

603858

Alternaria alternate; cat dander; Cladosporium herbarum; cockroach (German); codfish; D farina; D pteronyssinus; dog dander; egg white; milk; mouse urine; peanut (whole); shrimp; soybean; walnut; wheat

*If reflex testing is performed; additional charges/CPT code(s) may apply.

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