Retinol-binding Protein (RbP)

CPT: 83883
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Expected Turnaround Time

3 - 6 days


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Specimen Requirements


Specimen

Serum or plasma


Volume

1 mL


Minimum Volume

0.4 mL


Container

Red-top tube, gel-barrier tube, or green-top (heparin) tube


Collection

Separate serum or plasma from red blood cells.


Storage Instructions

Room temperature


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Gross lipemia that cannot be clarified by ultracentrifugation; heat-inactivated samples


Test Details


Use

Serum concentrations reflect the synthesis capacity of the liver and may indicate early malnutrition, acute and chronic hepatic disease, advanced chronic renal insufficiency, and cystic fibrosis. Assess nephritic syndrome and protein-losing enteropathy. Due to the short half-life of approximately 12 hours, RBP may be suitable for monitoring the nutritional status and efficacy of parenteral nutrition.1


Methodology

Immunologic


Reference Interval

See table.

Age

Range (mg/dL)

0 to 12 y

1.2−4.6

13 to 60 y

1.6−6.1

61 to 80 y

1.8−7.3

>80 y

1.6−6.1


Additional Information

Responsible for binding and transporting retinol (vitamin A).


Footnotes

1. Haider M, Haider SQ. Assessment of protein-calorie malnutrition. Clin Chem. 1984 Aug; 30(8):1286-1299.6430595

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
123060 Retinol binding Protein(RbP) 1836-6 123061 Retinol Binding Protein(RbP) mg/dL 1836-6

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