Prenatal Care
 LabCorp, a scientific leader in the field of diagnostic genetics, offers a broad  prenatal test portfolio to aid women's health care physicians in better patient care. LabCorp's prenatal program includes an extensive menu of biochemical, molecular, and cytogenetics testing. Some of the gene-based assays include cystic fibrosis, fragile X syndrome, and Tay-Sachs disease.
At LabCorp, our dedication to women's health and prenatal care is not only evidenced by the comprehensive test portfolio, but the services that extend beyond the test itself. Genetic counseling from board-certified genetic counselors and geneticists is available to assist in the interpretation of results or to recommend follow-up testing.
 Prenatal Genetic Information
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Maternal Serum Screening Maternal Serum Screening can identify pregnant women who are at increased risk for having a baby with certain birth defects. Patient-specific risks for open spina bifida, Down syndrome, and trisomy 18 (Edwards syndrome) can be determined by measuring the levels of certain proteins in maternal serum and combining those data with the patient's maternal age and clinical information.
LabCorp offers first trimester screening for Down syndrome and trisomy 18 that combines maternal serum levels of total human chorionic gonadotropin (hCG), pregnancy-associated plasma protein-A (PAPP-A), and dimeric inhibin A (DIA) with maternal age risk and a fetal nuchal translucency (NT) measurement.
First Trimester Screening: Early Screening for Down Syndrome
LabCorp's second trimester screening options include maternal serum AFP, AFP X-tra, and AFP Tetra.
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Cystic Fibrosis Cystic fibrosis (CF) is one of the most common genetic diseases in the Caucasian population. Approximately 1 in every 25 Caucasians is a carrier for this recessive condition. The American College of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics (ACMG) have recommended that carrier screening be offered to all Caucasian couples who are pregnant or considering pregnancy and made available to all patients.
LabCorp offers a panel of 32 of the most common CF mutations appropriate for routine carrier screening-including the 23 mutations recommended by the ACOG and the ACMG. LabCorp also offers an expanded panel of 70 mutations that may be of benefit in certain clinical situations.
Genetic Testing for Cystic Fibrosis
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Jewish Heritage Disorders The term Jewish Heritage disorders refers to a broad group of genetic disorders that are found at greater incidence, compared to the general population, among individuals of Jewish descent. Ashkenazi Jews can trace their ancestry to Western, Central, and Eastern Europe, and are more likely to be carriers of certain disease-associated genes.
The common genetic disorders often considered for Jewish heritage carrier screening during pregnancy include Tay-Sachs disease, Canavan disease, Cystic fibrosis, Familial dysautonomia, Fanconi anemia, Niemann-Pick disease, Gaucher disease, Bloom syndrome, and Mucolipidosis Type IV.
Jewish Heritage Carrier Screening
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Tay-Sachs Disease Tay-Sachs disease (TSD) is a lysosomal storage disorder that causes progressive neurological disease. TSD is an autosomal recessive disorder. Both parents must be carriers of TSD to have affected children. When both parents are carriers, they have a 25% chance with each pregnancy to have an affected child. LabCorp offers several test options for Tay-Sachs Disease.
Tay-Sachs Disease
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Fragile X Syndrome Fragile X syndrome is the most common cause of inherited mental retardation. The gene for fragile X syndrome is located on the X chromosome. Approximately one in 1200 males is born with the disease.
Fragile X Syndrome
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Group B Streptococcal Disease Group B Streptococcal Disease continues to be a major cause of illness and death among newborns. LabCorp's Group B Streptococcus Colonization Detection with Selective Broth Culture and DNA probe can report a positive or negative result up to 48 hours earlier than the standard broth culture test.
Group B Streptococcal Disease in the Newborn
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