<i>Leptospira</i> IgM Antibodies, EIA
| Leptospira IgM Antibodies, EIA | | | |
| Number | | 164970 |
CPT | | 86720 |
| Synonyms | | Canicola Fever ; Ft Bragg Fever ; Swamp Fever ; Weil Disease |
| Specimen | | Serum |
| Volume | | 0.4 mL |
| Minimum Volume | | 0.2 mL |
| Container | | Red-top tube or gel-barrier tube |
| Storage Instructions | | Refrigerate for up to 7 days; freeze for longer storage. |
| Causes for Rejection | | Hemolysis; lipemia; bacterial contamination |
| Reference Interval | | - Negative: <9 PanBio units
- Equivocal: 9-11 PanBio units
- Positive: >11 PanBio units
|
| Use | | Detect specific antibody of the IgM class to Leptospira genus-specific antigen. The presence of a significant or rising level of IgM is considered presumptive evidence of acute Leptospira infection. IgM antibodies appear as early as 3 days after infection and may persist for up to 5 months, or in rare cases, antibody may persist for years. |
| Limitations | | This test is designed as a screening test only, therefore, a small percentage of patients with other acute infections (eg, Q fever) may show a positive result. |
| Methodology | | Enzyme-linked immunosorbent assay (ELISA) |
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