Melanocyte-stimulating Hormone (MSH)

Melanocyte-stimulating Hormone (MSH)

Number
	010421
CPT
	83519
Synonyms
	Alpha-Melanocyte-stimulating Hormone ; MSH ; α-MSH Melanocyte-stimulating Hormone (MSH), Plasma
Special Instructions
	Contact LabCorp supply department for collection kit.
Specimen
	Plasma with Trasylol®, frozen
Volume
	2 mL
Minimum Volume
	0.3 mL
Container
	Lavender-top (EDTA) tube
Collection
	Collect 6 mL blood in a prechilled lavender-top tube. Transfer to a red-top tube containing 0.25 mL Trasylol® solution(10,000 KIU/mL). Mix well, centrifuge, transfer plasma to specially labeled transport tube and freeze. Trasylol® kits maybe ordered using LabCorp ID 33328.
Storage Instructions
	Freeze
Causes for Rejection
	Recently administered isotopes; specimen not frozen; serum specimen
Reference Interval
	0-49 pg/mL
Limitations
	This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.
Methodology
	Radioimmunoassay (RIA)
References
	Catania A, Airaghi L, Garofalo L, et al, “The Neuropeptide Alpha-MSH in HIV Infection and Other Disorders in Humans,” Ann N Y Acad Sci, 1998, 840:848-56. Clark D, Thody AJ, Shuster S, et al, “Immunoreactive α-MSH in Human Plasma in Pregnancy,” Nature, 1978, 273(5658):163-4. Krieger DT, Liotta AS, Brownstein MJ, et al, “ACH, Beta-Lipotropin and Related Peptides in Brain, Pituitary, and Blood,” Recent Prog Horm Res, 1980, 36:277-344. Reid RI, Lina N, and Yen SS, “Alpha-Melanocyte Stimulating Hormone Induces Gonadotropin Release,” J Clin Endocrinol Metab, 1981, 52(1):159-61.