Postpartum 75-Gram Glucose Tolerance

Postpartum 75-Gram Glucose Tolerance

Number
	101675
CPT
	82951; 82952 (x2)
Synonyms
	Glucose Tolerance, Postpartum ; Oral Glucose Tolerance Test (OGTT) ; O'Sullivan Postpartum Replaced by Recommendations From the Fourth International Workshop-Conference
Test Includes
	75-g 2-hour oral glucose tolerance test
Specimen
	Serum or plasma
Volume
	2 mL in each tube
Minimum Volume
	0.5 mL serum, 1 mL plasma
Container
	Gel-barrier tube or gray-top (sodium fluoride/potassium oxalate) tube (separate blood within 45 minutes of collection)
Collection
	Administer 75-g glucose and draw blood fasting, at 30 minutes, 1 hour, 1.5 hours, and 2 hours. The subject should remain seated and not smoke throughout the test. Submit 2 mL serum or plasma for fasting, 30 minutes, 1 hour, 1.5 hours, and 2 hours. Separate serum or plasma from cells within 45 minutes of collection. Label each tube with patient's name and time interval.
Storage Instructions
	Refrigerate
Patient Preparation
	Patient should not smoke, but should be active and eat a regular diet that includes at least 150 grams of carbohydrate daily for 3 days, and then fast 12 hours prior to the test. Many drugs interfere with test results. The patient should not be stressed.
Causes for Rejection
	Nonfasting patient; improper labeling
Reference Interval
	See the Endocrine Appendix for further information regarding glucose tolerance testing.
Use
	Postpartum evaluation of women previously diagnosed with gestational diabetes mellitus
Methodology
	Enzymatic
Contraindications
	Patient with known history of diabetes mellitus
References
	American Diabetes Association, “Postpartum Follow-up of Women With Gestational Diabetes,” Medical Management of Pregnancy Complicated by Diabetes, Banks P, ed, Alexandria, VA: American Diabetes Association, 1993, 103-5. Lind T, Phillips PR, and the Diabetic Pregnancy Study Group of the European Association for the Study of Diabetes, “Influence of Pregnancy on the 75-g OGTT, A Prospective Multicenter Study,” Diabetes, 1991, 40(Suppl 2):8-13. Magee MS, Walden CE, Benedetti TJ, et al, “Influence of Diagnostic Criteria on the Incidence of Gestational Diabetes and Perinatal Morbidity,” JAMA, 1993, 269(5):609-15. Metzger BE and Coustan DR, “Summary and Recommendations of the Fourth International Workshop-Conference on Gestational Diabetes Mellitus,” Diabetes Care, 1998, 21(Suppl 2):B161-7. “National Diabetes Data Group: Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance,” Diabetes, 1979, 28(12):1039-57. “Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus,” Diabetes Care, 1997, 20(7):1183-97.