Ureaplasma/Mycoplasma hominis Culture
| Ureaplasma/Mycoplasma hominis Culture | | | |
| Number | | 086884 |
| CPT | | 87109 |
| Synonyms | | Culture, Mycoplasma hominis (genital specimens) ; Culture, Ureaplasma urealyticum, Genital ; Mycoplasma hominis Genital Culture ; Mycoplasma T-Strain Culture, Genital ; Ureaplasma Culture |
| Test Includes | | Culture; isolation and identification if culture results warrant (additional charges/CPT code[s] may apply). CPT coding for microbiology and virology procedures often cannot be determined before the culture is performed. |
| Special Instructions | | Submit one specimen per test requested. Specify the exact specimen source/origin (eg, genital lesion). Indicate a specific test number on the request form. |
| Specimen | | Endocervical exudates or scrapings, urethral exudate, urine, endometrial washing or biopsy, fallopian tube, placenta, fetal part, semen; blood or cerebrospinal fluid from neonates |
| Container | | Viral, Chlamydia, or Mycoplasma culture transport provided by LabCorp, or other appropriate transport medium |
| Collection | | - Male: Collect urethral specimen on viral culture, small-tipped swab blue cap. Refrigerate and ship at 4°C.
- Female: Collect vaginal and urethral specimens with viral culture collection swab blue cap. Refrigerate and ship at 4°C.
- Semen/urine: Collect specimen in sterile, leakproof container.
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| Storage Instructions | | Refrigerate and ship at 4°C. |
| Causes for Rejection | | Bacterial swab specimen; specimen received in grossly leaking transport container; dry specimen; specimen submitted in fixative or additive; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions; specimen received after prolonged delay in transport (usually more than 72 hours); specimen stored or transported at room temperature; wooden shaft swab in transport device; unlabeled specimen or name discrepancy between specimen and request label |
| Use | | Establish the diagnosis of Ureaplasma urealyticum infection in suspected cases of urethritis and cervicitis |
| Limitations | | Culture may be negative in the presence of infection, and the presence of Ureaplasma urealyticum or Mycoplasma hominis does not always indicate infection, although there is a significant association with symptomatic disease. |
| Methodology | | Culture on selective media1 |
| Additional Information | | Ureaplasma and Mycoplasma can be isolated from urethral and genital swabs and from urine of sexually active individuals. Sixty percent or more of all women asymptomatically carry U. urealyticum in their genital tract. Usual prevalence of these organisms in patients with urethral symptoms also is high; thus, conclusions regarding the etiologic role of an isolate in a given patient are difficult to make. Nevertheless, Ureaplasma urealyticum has been associated with cases of nongonococcal urethritis. |
| Footnotes | | - Leland DS, Lapworth MA, Jones RB, et al, “Comparative Evaluation of Media for the Isolation of Ureaplasma urealyticum and Genital Mycoplasma Species,” J Clin Microbiol, 1982, 16(4):709-14
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| References | | Bell TA, “Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum Infections of Infants,” Semin Perinatol, 1985, 9(1):29-37. Stamm WE, Wagner KF, Amsel R, et al, “Causes of the Acute Urethral Syndrome in Women,” N Engl J Med, 1980, 303(8):409-15. Taylor-Robinson D and McCormack WM, “The Genital Mycoplasmas,” N Engl J Med, 1980, 302(18):1003-10 (review). |
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