Xylenes, Blood
| Xylenes, Blood | | | |
| Number | | 723106 |
| CPT | | 84600 |
| Related Information | | Aromatic Solvents Exposure, Blood Xylenes Exposure Profile Xylenes Metabolite Profile, Urine |
| Test Includes | | Xylenes (o-, m-, p-xylene), blood |
| Specimen | | Whole blood |
| Volume | | 7 mL |
| Minimum Volume | | 1.1 mL |
Container | | Lavender-top (EDTA) tube. Submit original full,
unopened tube. |
| Collection | | Venipuncture site must be disinfected with povidone-iodine or a similar product. |
| Storage Instructions | | Refrigerate |
| Causes for Rejection | | Opened tube or pour-off; clotted specimen |
| Reference Interval | | - Environmental exposure: none detected
- Occupational exposure: Levels of 1.0 mg/L were found to be consistent with exposure to 100 ppm. The current recommended allowable threshold limit value (TLV®) for air concentration is 100 ppm.
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| Use | | Monitor exposure to xylenes |
| Methodology | | Gas chromatography (GC) |
| Additional Information | | Xylene exposure to concentrations of 200 ppm and up can cause nausea, mucous membrane irritation, dizziness, incoordination, and impairment of equilibrium. Elevated concentrations (approximately 10,000 ppm) may produce significant CNS depressant effects such as unconsciousness.1 Xylene is often found in the industrial environment as a component of the petroleum hydrocarbon solvents used in paints, lacquers, cleaning agents, pesticides, and gasoline. Blood is the preferred specimen for monitoring an acute or recent exposure. |
| Footnotes | | - Baselt RC and Cravey RH, Disposition of Toxic Drugs and Chemicals in Man, 4th ed, Chemical Toxicology Institute, 1995
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